3T Core Structure

The head of the 3T Core Structure, Ralf Deichmann, studied physics at the University of Würzburg, Germany, and at the State University of New York, Albany, USA. He specialized in MR physics during his Diploma and PhD theses, developing cutting-edge methods for quantitative relaxometry. Subsequently, he worked in the Wellcome Department of Imaging Neuroscience of UCL, London, UK, where he created numerous techniques for improved functional, structural and Diffusion Tensor imaging. Since 2007, he holds a Full Professorship for Experimental MR Tomography in the Neurosciences at Goethe University, Frankfurt, Germany. His main research focus is on quantitative MR Imaging (qMRI) which allows the measurement of various tissue parameters. His work comprises the development of qMRI acquisition techniques, the creation and maintenance of a qMRI data analysis package and the application of tissue parameter maps for the calculation of synthetic MR images with improved contrasts, e.g. for highlighting certain brain pathologies.

Ulrike Nöth studied physics at the University of Würzburg and at the State University of New York at Albany, USA. This was followed by a PhD project in the field of 19F MRI supervised by Axel Haase and a postdoctoral position at the Institute of Physiology (both University of Würzburg). She then spent a two-year DFG-funded research stay as a postdoc in the lab of John Griffiths at the St. George’s Hospital Medical School in London, UK. In 2001 she moved on to the Helmholtz Center in Munich where she headed the 9.4 Tesla MR lab. From 2002 to 2005 she was granted a sabbatical stay in London, UK, working on a collaboration project of the National Heart and Lung Institute (Imperial College) and the Wellcome Department of Imaging Neuroscience (IoN, UCL) combining EEG and MRI for the measurement of cerebral perfusion with ASL during sleep. In 2009, she became a member of the 3T core structure at the BIC (now CoBIC) in Frankfurt. Her main interest is in the field of quantitative MRI (methods and applications).

As an MRI physicist and member of the 3T MRI Core structure, Manoj Shrestha specializes in advanced magnetic resonance imaging methods for human brain research. His research focuses on functional, structural, and quantitative MRI, as well as diffusion, perfusion, and CEST imaging techniques. His expertise includes the development of novel MRI pulse sequences, image reconstruction programming, and comprehensive image data analysis. He is also highly experienced in optimizing MRI sequences and protocols to enhance image quality, robustness, and efficiency.

Since 2015, he has been working as an MRI Physicist at the Brain Imaging Center (BIC) at Goethe University Frankfurt, Germany, which was converted into the Cooperative Brain Imaging Center (CoBIC) in 2024. He received his PhD in Neurophysics in 2016 from the Institute for Medical Physics and Biophysics at the University of Leipzig, Germany. From 2010 to 2014, he conducted his doctoral research at the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig, Germany.

Nadine Brüche completed her training as an MTRA in Leipzig in 2004. In 2006 she got her first experience in MRI and started to specialise in the field.
Since 2019, Nadine has been working for the 3Tesla core structure of the Brain Imaging Center. She supports researchers in their MRI-based research
and is responsible for safety concerning the 3 Tesla MRIs. Nadine also takes care of administrative and organisational tasks for the 3Tesla core structure.

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